https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45027 HFE, TFR1, HAMP, TF, SOD2, CAT and GPX1. Results: Lung cancer patients compared to their matched controls had significantly higher mean serum iron level (p = 0.01), ferritin level (p = 0.007) and TIBC (p = 0.006). Analysis revealed that higher concentration of iron and ferritin (IVth quartile) compared to the lower concentration (Ist quartile) was associated with over 2-fold increased lung cancer incidence. We also found that higher transferrin saturation (p = 0.01) and lower TIBC (p<0.01) are associated with better survival of lung cancer patients. The analysis of polymorphisms in iron related genes did not reveal a significant difference between lung cancer patients and controls. However, rs10421768 in HAMP showed a borderline statistically significant correlation with lung cancer risk (OR = 2.83, p = 0.05). Conclusions: The results of this case control study indicate that higher body iron represented by higher Fe and ferritin levels may be associated with lung cancer incidence. Rs10421768 in HAMP may be associated with about 3-times higher lung cancer risk. Higher Fe body content may be associated with better survival of lung cancer patients]]> Wed 26 Oct 2022 11:09:17 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:27053 Wed 11 Apr 2018 16:37:42 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:14831 Wed 11 Apr 2018 13:24:36 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:16770 Wed 11 Apr 2018 10:04:45 AEST ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:35067 853.0–973.9 μg/l). Among five analyzed genetic variants, rs11568818 in MMP-7 appeared to be correlated with 2-fold increased prostate cancer risk (OR = 2.39, 95% CI = 1.19–4.82, p = 0.015). Conclusion: Our results suggest a significant correlation of higher serum zinc levels with the diagnosis of prostate cancer. The polymorphism rs11568818 in MMP-7 gene was also associated with an increased prostate cancer risk in Poland.]]> Thu 04 Nov 2021 10:38:46 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:19105 Sat 24 Mar 2018 07:55:58 AEDT ]]> https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25547 Sat 24 Mar 2018 07:26:05 AEDT ]]>